By Suzanne L. Iverson,Dennis A. Smith

A reference on drug metabolism and metabolite defense within the improvement part, this e-book stories the analytical suggestions and experimental designs severe for metabolite experiences. It beneficial properties case reports of classes discovered and genuine international examples, in addition to regulatory views from the USA FDA and EMA.

•    Reviews the analytical ideas and experimental designs serious for metabolite studies
•    Covers tools together with chirality, species alterations, mass spectrometry, radiolabels, and in vitro / in vivo correlation
•    Discusses objective pharmacology, in vitro platforms aligned to toxicity assessments, and drug-drug interactions
•    Includes views from authors with firsthand involvement in and the examine of drug metabolites, together with viewpoints that experience stimulated regulatory guidelines

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