By Morteza Vaghefi

Used largely in mobile and molecular biology study and cytogenetic functions, nucleotide analogs are presently to be had for the therapy of assorted ailments. Nucleoside Triphosphate and Their Analogs: Chemistry, Biotechnology, and organic purposes good points the contributions of 18 scientists from either academia and within the first whole resource committed solely to nucleoside triphosphate (NTP). The textual content presents collective details at the chemical, physiochemical, and organic homes of either traditional and transformed NTP along their software in lifestyles sciences.

This e-book examines the structural parts of NTPs' varied organic homes and healing effects, together with cytotoxic compounds, antiviral brokers, and immunosuppressive molecules. The textual content describes artificial tools used for every type of nucleotides and reports households of enzymes that rely on nucleotides for assembling DNA and RNA molecules. This e-book additionally emphasizes the main position NTP performs within the worldwide monitoring of conformational alterations in nucleic acids and nucleic acid complexes and the research of mobile methods and genetic fabric. the writer info the pharmaceutical and diagnostic functions of NTP amendment and the way fluorescent categorized nucleotide analogs supply delicate probes for learning the constitution, dynamics, and interactions of nucleic acids.

Nucleoside Triphosphate and Their Analogs: Chemistry, Biotechnology, and organic purposes discusses the opportunity of present purposes and destiny examine into context with an in-depth research of the position anticancer and antiviral nucleoside analogs play in scientific remedies, together with antiretroviral remedy regimens (for the therapy of HIV), anti-rejection treatment for organ transplants, hematological malignancy remedy, and the therapy of nonmalignant issues, good tumors, immunologic illnesses, and a number of sclerosis.

Show description

Read Online or Download Nucleoside Triphosphates and their Analogs: Chemistry, Biotechnology, and Biological Applications PDF

Best organic chemistry books

Every Molecule Tells a Story

From cooking to drugs, from engineering to paintings, chemistry—the technological know-how of molecules—is all over. a party of the molecules of chemistry, each Molecule Tells a narrative celebrates the molecules chargeable for the stories of lifestyle: the air we breathe; the water we drink; the chemical compounds that gas our dwelling; the steroids that supply us intercourse; the colors of the seasons; the medication that heal us; and the scented molecules that increase our nutrition and our encounters with one another.

Review of Organic Functional Groups: Introduction to Medicinal Organic Chemistry

With its pupil Workbook CD-ROM and new case reports, the 5th version of this acclaimed self-paced evaluation permits scholars to grasp the rules and functions of natural practical teams. in addition, it prepares scholars for the mandatory pharmacy classes in medicinal chemistry through completely protecting nomenclature, actual houses, chemical homes, and metabolism.

Chemistry of Plant Phosphorus Compounds

Presents a excessive point reference resource for scientists engaged in any point of plant learn − chemistry, biochemistry or body structure − with basic specialize in the chemistry of phosphorus-containing compounds that happen obviously within the plant state, and in particular within the larger crops (Plantae). The e-book is accomplished with admire to nomenclature, actual houses, and distribution all over the world.

Modern Synthetic Methods in Carbohydrate Chemistry: From Monosaccharides to Complex Glycoconjugates

The fields of glycochemistry and glycoscience are wealthy and sundry and the place a lot might be realized from Nature. As Nature isn't constantly in a position to produce carbohydrates in amounts necessary for not just in study but additionally as healing brokers, new methods must be chanced on to optimize the yield. This ebook provides an outline of the most recent advancements within the box of carbohydrates, starting from de-novo ways through cyclodextrin chemistry to the synthesis of such hugely complicated glycoconjugates as glycosphingolipids and GPI anchors.

Extra info for Nucleoside Triphosphates and their Analogs: Chemistry, Biotechnology, and Biological Applications

Example text

Download PDF sample

Rated 4.06 of 5 – based on 19 votes